Metabolism
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Selection of fuels for muscle contraction
Objectives
After this exercise, you should be able to:
Describe and explain the sources and metabolism of the different fuels available to muscle (muscle glycogen, blood glucose, triacylglycerol from plasma lipoproteins, plasma non-esterified fatty acids, and ketone bodies);
Explain how the intensity of physical work influences muscle fuel selection
Explain how metabolic state (fed or fasting) influences muscle fuel selection
List and explain the regulatory mechanisms involved in muscle fuel selection under different conditions
Explain the role of creatine phosphate in muscle contraction
Explain the difference between aerobic and anaerobic exercise, and the relative importance of each in weight reduction and prevention of obesity.