Metabolism on-line - the virtual tutorial room
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Transamination and deamination of amino acids
Objectives
At the end of the session you should be able to:
Describe the reaction of transamination and the role of pyridoxal phosphate as the prosthteic group of transaminases
Describe the reactions involved in overall deamination of various amino acids linked to glutamate dehydrogenase and aspartate transaminase
Explain how the keto-acids of essential amino acids can be used in treating patients in renal failure
Expain how red blood cell transaminases can be used to assess vitamin B6 nutritional status