Metabolism
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An unusual cause of diabetes - how the pancreas senses a rise in blood glucose
Objectives
After this exercise you should be able to:
Explain what is meant by isoenzymes
Explain how the Km of an enzyme, relative to the concentration of the substrate, affects the rate of reaction
Explain the importance of glucokinase in the liver
Explain how the pancreas senses an increased concentration of glucose in the portal blood, and how this acts as a signal for secretion of insulin.